AMIGO

Advanced Medical Intelligence for Guiding Orphan Medicine

Challenge

We invite you to develop machine learning (ML) algorithms that can use knowledge graph data and accomplish these points:​

A. Accurately predict if a child is healthy or is diagnosed with an illness.​

B. Accurately predict patients’ disease category based on the first letter of ICD-10 code system.​

C. Correctly Cluster patients based on the features from the omics and clinical data.​

D. Offer the capability to be executed federatively using the feature cloud functionality.​

Business Outcome

  • Outline how the approach can be implemented and scaled to improve patients’ lives.​

Technical Architecture

  • You are free to use the synthetic data made available for you on Neo4j data base
  • You will be able to connect to the Feature Cloud platform and upload your models
  • You are free to use both supervised and unsupervised methods.

Technical Architecture

Background

  • The disease experts at the Dr. von Hauner Children’s Hospital in Munich are working toward establishing an AI platform to improve diagnosis of rare diseases in children. ​

  • Their goal is to implement federated learning and create a library of ML models to assist clinicians with patients’ diagnosis.​

  • To protect patients’ privacy, we have already preprocessed and analyzed the data and created knowledge graphs which you can use to build your algorithm. ​

  • The knowledge graph data comprise thousands of human phenotype ontology (HPO) features, covering genomic, proteomic, blood values, electronic health records and patient questionnaires.​

  • Additionally, we provide you with a well-crafted unlabeled synthetic data set that closely resembles the structure of the real data.​

Joint initiative of

Last modified April 24, 2024: Little changes, fixing bugs (5ecf6fa)